Written By Anna Avaliani,
What is JEUVEAU (prabotulinumtoxinA-xvfs)?
In US it’s called Jeuveau and in South Korea it’s known as Nabota
It’s simply another neuromodulator on the market which helps to soften and relax angry lines between the eyebrows called as frown limes or glabella lines.
We know it’s safe, we know it works by the same mechanism as Botox, Dysport or Xeomin by temporary relaxing the muscle.
What is so special about Jeuveau?
It’s is difficult to say now, but new doesn’t necessarily mean good and more time is needed to really see how well this new neurotoxin compares to two current pioneers on the field Botox and Dysport
The most updated list of currently FDA approved Neuromodulators on the market
| Neurotoxins | JEUVEAU | Dysport | Botox | Xeomin | Myobloc |
| prabotulinumtoxinA-xvfs | abobotulinumtoxinA | onabotulinumtoxinA | incobotulinumtoxinA | rimabotulinumtoxinB | |
| Toxin Type | A | A | A | A | B |
| On label common use | Glabella | Glabella and crows feet | Glabella, crows feet, forehead | Glabella | Neck muscles |
| Became available | 2019 | 2007 | 2002 | 2012 | 2015 |
| Duration | 3-4 months | 3-4 months | 3-4 months | 2-3 months | 3-4months |
| Onset of action | 4-7 days | 4-7 days | Up to 14 days | Up to 14 days | Up tp 14 days |
| Units | Minimal dose is 20 | Minimal dose is 50 | Minimal dose is 20 | Minimal dose is 20 | 2500 units |
How is JEUVEAU administered?
It’s administered as an injection medication. 5 tiny pricks between the eyebrows to achieve temporary relaxation of the muscle
What is the optimal dose of Jeuveau?
20 units is the minimum amount that must be administered in order to achieve results. 20 units may not be optimal for some patients and they may require more. How much more actually depends on the strength of the muscle and the original effect achieved with the initial dose.
How long does it take after JEUVEAU administration to show results?
The onset starts around 4 days and it may up to 14 days after the initial injection to achieve full response/relaxation.
How long does JEUVEAU injection procedure take?
It is a fairly simple and quick procedure in the hands of an expert. No numbing or other special patient preparation is required. In the hands of an expert, it takes about 1 minute.
Dr.Avaliani uses the smallest and thinnest needles on the market to ensure highest patient comfort. She also is utilizing her vein finder tool, to minimize any chance of bruising.
How long do JEUVEAU results last?
The average duration of JEUVEAU neuromodulator after the optimal dose administration was reported to be between 3-4 months, just like other neurotoxins currently available on the market
What is the difference between JEUVEAUâ and Nabotaâ?
JEUVEAU is FDA approved for US market administration and Nabota is approved in South Korea. It is manufactured by the same company and different names are simply for the marketing purposes and different packaging. They are both same medication made from prabotulinumtoxinA-xvfs tonin strain.
What is the difference between JEUVEAU and Botox?
They are essentially the same class of medications, under a class of neurotoxins. They both produced from Toxin type A and administered by an injection with similar efficacy and duration intervals. They are just like Coke and Pepsi. Some people don’t care. Others, feel the taste difference.
What is the difference between JEUVEAU and Dysport?
The difference is in the name of the toxin and the dosage administered, but for a patient, the efficacy is essentially the same. Patient should try both and determine if they have preference and if they notice any difference in the effect and well as the duration of the product.
What is the difference between JEUVEAU and Xeomin?
These medications are made by different companies, they use different bacteria strains but both use Type A Toxin. They both require an injection for preparation and safety and efficacy is very similar.
What is the difference between JEUVEAU and Myobloc?
They belong to the same class of drugs, but they have very different characteristics. JEUVEAU is type A toxin, while Myobloc is Type B toxin. Their dosage units are different and cannot be interchanged, 20 units of JEUVEAU is almost like 2500 units of MyoBloc. Please leave it up to your healthcare professional to determine your optimal dosing.
What are the most common side effects with JEUVEAU administration?
Redness, tenderness at the injection site, bumps, bruising are all common and very mild side effects reported immediately after the injection.
To receive your expert consultation with Dr.Avaliani to determine whether JEUVEAU is right for you, please call 212-673-8888 .