Pro-Nox

The Pain-Free, Anxiety-Free Treatment Experience You Deserve

Expertise

Top 1%
Injector in US

Experience

11+ Years
12k + Patients

Excellence

36+ Top lasers
25+ Injectables

Why Choose Dr. Avaliani for the Pro-Nox Experience?

Dr. Avaliani believes every aesthetic treatment should be comfortable and anxiety-free. Pro-Nox is a self-administered nitrous oxide system that delivers a 50/50 blend of nitrous oxide and oxygen, allowing patients to relax, reduce anxiety, and eliminate discomfort during any cosmetic procedure. Available for every treatment at no mandatory upcharge — it is the foundation of the Dr. Avaliani Experience.

Self-Administered Comfort

You control your own comfort level with a simple mouthpiece — breathe in when you want relief, stop when you feel comfortable

Board-Certified Physician

11+ years of experience ensuring patient comfort and safety during every treatment

Universal Compatibility

Pro-Nox can be used with virtually any treatment — from BOTOX and fillers to lasers, body contouring, and thread lifts

A Reputation Built on Results

5.0-star rating with 565+ verified reviews emphasizing the comfort of the treatment experience

Zero Recovery Time

Effects wear off completely in under 10 minutes — you can drive yourself home and return to all normal activities immediately

Dr. Avaliani will discuss Pro-Nox with you during your consultation to ensure your treatment experience is as comfortable and anxiety-free as possible.

What Is Pro-Nox?

Pro-Nox is a patient-controlled inhaled analgesia system that delivers a fixed 50/50 mixture of nitrous oxide and oxygen gas. It provides immediate anxiety relief and pain reduction during cosmetic procedures without sedation, needles, or opioids. The patient self-administers through a disposable mouthpiece, controlling exactly how much comfort they need at any moment.

At Dr. Avaliani’s practice, Pro-Nox is the cornerstone of the comfort experience. It works within 2–3 minutes of inhalation, producing slight euphoria and deep relaxation that reduces pain perception through analgesia — not full anesthesia. You remain fully awake, alert, and in control throughout your treatment.

How Pro-Nox Works

The Pro-Nox experience is simple and patient-controlled:

A disposable mouthpiece is provided — you breathe normally through it whenever you want comfort

The fixed 50/50 nitrous oxide and oxygen blend takes effect within 2–3 minutes

You experience gentle euphoria and relaxation — reducing anxiety and pain perception

You control the intensity by breathing in more or less through the mouthpiece

Effects wear off completely within 10 minutes after you stop breathing through the mouthpiece — no lingering drowsiness

Treatments Enhanced by Pro-Nox

Injection Anxiety

Nervous about needles? Pro-Nox calms anxiety before BOTOX, Dysport, and dermal filler injections, making the experience comfortable and stress-free.

Laser Treatment Comfort

Laser procedures like PicoSure, tattoo removal, and skin resurfacing are more comfortable with Pro-Nox reducing pain perception during treatment.

Body Contouring Sessions

Longer procedures like CoolSculpting, SculpSure, and Emsculpt NEO are more relaxing with Pro-Nox available throughout your session.

Microneedling & RF

Microneedling, Genius RF, and Morpheus8 treatments involve micro-pinprick sensations that Pro-Nox effectively minimizes for a comfortable experience.

Thread Lift Procedures

PDO thread lifts involve multiple insertion points. Pro-Nox provides continuous comfort control throughout the entire procedure.

First-Time Patients

If you’ve never had an aesthetic treatment before, Pro-Nox eliminates the fear of the unknown, making your first experience positive and anxiety-free.

Our Comfort Technologies

Dr. Avaliani offers multiple comfort technologies to ensure every treatment is a positive experience. Here’s what sets her practice apart:

Pro-Nox™ System
The leading patient-controlled nitrous oxide delivery system. Fixed 50/50 N₂O/O₂ blend via disposable mouthpiece. Self-administered, non-addictive, FDA-cleared. Effects in 2–3 minutes, gone in under 10. Used with any cosmetic procedure.
NitroNox™ System
Identical gas delivery mechanism to Pro-Nox — same 50/50 nitrous oxide and oxygen blend via patient-controlled disposable mouthpiece. Both systems provide the same comfort experience.
AccuVein® Technology
Advanced vein visualization complements Pro-Nox for the ultimate comfort experience. AccuVein maps blood vessels in real time to virtually eliminate bruising during all injection procedures.

Does It Hurt?

Your Comfort Options (We Tailor This to You)

Pro-Nox IS the comfort solution. When using Pro-Nox during your treatment, most patients describe the experience as completely comfortable — even relaxing. The nitrous oxide creates a gentle sense of euphoria that significantly reduces pain perception without sedation. You remain fully aware and in control throughout.

Pro-Nox itself requires zero recovery time. All effects wear off within 10 minutes after you stop breathing through the mouthpiece. You can drive yourself home, return to work, and resume all normal activities immediately. No designated driver needed.

Feel Calm. Stay in Control. Look Amazing.

Reduced Anxiety

Settle into a calm, relaxed state before and during your treatment — no stress, no tension.

Less Discomfort

Enhanced comfort for your treatment, so you can focus on your results.

No Downtime

Walk out feeling great and drive yourself home — absolutely no recovery time required.

PRO-NOX

Nitrous Oxide

Available On Request

For patients who prefer an extra layer of relaxation, Pro‑Nox™ provides a gentle, calming effect that wears off instantly. Most patients find their treatments very manageable — but it’s always here if you want it.

View Before &
After Gallery

Is Pro-Nox Right for Me?

Ideal Candidates

You may be a good candidate if you:

Experience anxiety about needles or cosmetic procedures

Want maximum comfort during injectable treatments

Are undergoing longer procedures like laser treatments or body contouring

Prefer to avoid oral medications or opioids for comfort

Want to remain fully awake and in control during treatment

Are a first-time patient wanting a positive, stress-free introduction

What Does Pro-Nox Cost?

Pricing Information

Pro-Nox is available as an add-on to any treatment. Pricing varies — ask about Pro-Nox when scheduling your appointment.

Price Range:
Many patients find it invaluable for their comfort and continue requesting it for every visit

During your consultation, Dr. Avaliani will discuss Pro-Nox availability and pricing so you can make an informed decision about your comfort during treatment.

*Medical Disclaimer
Individual results may vary. No guarantee of specific results can be given. The degree of side effects and duration of results may vary. Content is for informational
purposes and does not substitute for professional medical advice provided during an in-office consultation and examination by a physician.

Luxury Treatments.
Flexible Payment Options.

Your Confidence Should Never Have to Wait.

At Anna Avaliani MD Cosmetic & Laser Surgery, we believe exceptional aesthetic care should be accessible when you are ready — not months or years later. That’s why we offer elegant financing solutions that allow you to begin your transformation today while comfortably managing the investment over time. Because confidence is priceless — and now it’s flexible.

Pro-Nox Frequently Asked Questions

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